Calcium propionate is an organic salt that helps preserve food by interfering with the ability of microorganisms, such as molds and bacteria, to reproduce. An animal study showed that feeding rats 1—3 grams of calcium propionate daily over 4—5 weeks had no impact on growth 8. Most lab studies on calcium propionate and toxicity came back negative, except for a few that used exceptionally high amounts.
For example, in one of these studies, researchers injected high amounts of calcium propionate into the yolk sacs of chicken embryos, resulting in abnormalities 7.
Instead, the substance is broken down by your digestive tract and readily absorbed, metabolized, and eliminated 7. In rare situations, it may cause adverse effects, such as headaches and migraines 9. One human study linked propionate intake to the increased production of insulin and glucagon, a hormone that stimulates glucose sugar release.
This can lead to insulin resistance, a condition in which your body cannot use insulin properly, which may lead to type 2 diabetes In addition, a study in 27 children found that some experienced irritability, restlessness, poor attention, and sleep issues after consuming calcium-propionate-containing bread daily However, more human studies are needed in these areas before it can be determined that calcium propionate causes these effects.
In general, calcium propionate is safe for most people, but in rare instances, some people may experience side effects. Calcium propionate is an organic salt that is used as a food additive. It helps preserve foods, mainly baked goods, by interfering with the growth and reproduction of microorganisms, such as molds, bacteria, and fungi.
In rare instances, people may experience headaches or migraines. While some studies have demonstrated connections between propionate and both negative behavioral effects in children and insulin resistance, more research is needed to determine whether propionate caused these effects.
Propylene glycol is commonly used as a food additive and ingredient in cosmetic products. Propionate acids occur naturally in cheese and butter, per the FDA. They're a short-chain fatty acid, according to the American Council on Science and Health. Calcium propionate is the calcium salt of propionic acid, while sodium propionate is the sodium salt of that same acid. Calcium propionate and sodium propionate are antifungal and also help stop the growth of certain bacteria, according to the FDA.
The FDA evaluated this preservative in In , a panel of the European Food Safety Authority assessed extending the use of sodium propionate, which was already in use in bakery and cheese products, to processed meat and fish. As you can see, organizations around the world that overlook the safety of food additives and preservatives have deemed calcium and sodium propionate safe to eat. Still, you may wonder if there are any harmful side effects to preservatives.
With these two, there's probably no cause for concern. Food and Drug Administration. Updated February 6, Pongsavee M. Effects of del A Ter frameshift mutation and calcium propionate on oxidative stress and breast carcinogenesis. Int J Mol Epidemiol Genet. Updated April 1, National Center for Biotechnology Information. Calcium propionate compound. Your Privacy Rights.
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